Ghimas Fisiograft Nano HA Reinforced - Bone Regeneration Material - 2x1ml

Fisiograft Nano H.A. consists of a granular structure placed in a syringe, allowing direct application to bone defects. The granules are made from a composite material of nanohydroxyapatite and polylactic-polyglycolic copolymer. These components have been used for years in space maintainers for guided bone tissue regeneration.

How it Works

FISIOGRAFT nano-H.A. reinforced allows permeation with blood from host tissues, and thanks to the presence of nanometric hydroxyapatite, it becomes a nucleus for the ossification of new bone tissue in the application area. The granules are specifically made from a nanohydroxyapatite-dextran composite material, with a polylactic-polyglycolic copolymer mixture serving as a carrier.

Osseointegration

• Achieves osseointegration within 6–9 months.

Product Specifications

• Composition:
  • Hydroxyapatite: 47% (470 mg)
  • PLGA: 5% (50 mg)
  • Dextran: 18% (180 mg)
  • PEG: 30% (300 mg)
• Granule Size: 70-100 nm
• Packaging: 2x1ml syringes

Hydroxyapatite Technology

• Patented production process.
• Characteristics that mimic the structural, dimensional, and biofunctional properties of natural hydroxyapatite found in dentin, cementum, and bone.
• Non-resorbable structure that provides osseointegration.
• Less inflammatory compared to normal hydroxyapatite.
• Leads to increased production of bone alkaline phosphatase and osteocalcin, indicating enhanced bone production.

Clinical Results

FISIOGRAFT NANO HA REINFORCED is ready for use. Histomorphometric analysis demonstrates the presence of 42% newly formed bone, 21% nano-hydroxyapatite, and 37% medullary spaces. This significant result was achieved just four months after surgery. This value is comparable to results obtained with autologous bone or other space maintainers after 6–8 months, as documented in the literature (2, 3).

Advantages of FISIOGRAFT NANO HA REINFORCED

• Resorption + Osseointegration:
  • Degradation of PLGA within 3–6 months to create space for newly formed bone.
  • Integration of hydroxyapatite with the mineralized structure of the bone.
• Risk-Free: Tested for BSE – HIV – HBV – SARS
• High biocompatibility
• Easy application