Ghimas Fisiograft Nano HA Reinforced - Bone Regeneration Material - 2x1ml

Fisiograft Nano H.A.

• Consists of granules placed in a syringe, enabling direct application to the bone defect.
• Granules are produced from a nanohydroxyapatite and polylactic-polylglycolic copolymer composite material.
• These components have been used for years in space maintainers for guided bone tissue regeneration.
• It permeates with blood from host tissue and, thanks to the presence of hydroxyapatite, becomes a support for ossification of new bone tissue at the application site.

FISIOGRAFT nano-H.A. reinforced

• Consists of granules placed in a syringe, enabling direct application to the bone defect.
• Granules are produced from a nanohydroxyapatite-dextran composite material with a polylactic-polylglycolic copolymer mixture used as carrier.
• Components have been used for years in space maintainers for guided bone tissue regeneration.
• It permeates with blood from bone and, thanks to the presence of nanometric hydroxyapatite, becomes a nucleus for ossification of new bone tissue at the application site.

OSSEOINTEGRATION IN 6–9 MONTHS

• Composition: Hydroxyapatite 47% (470 mg), PLGA 5% (50 mg), Dextran 18% (180 mg), PEG 30% (300 mg)
• Granule size: 70><100 nm
• Packaging: 2x1ml syringe

HYDROXYAPATITE

• Patented manufacturing process
• Characteristics that mimic the structural, dimensional and biofunctional properties of natural hydroxyapatite found in dentin, cementum and bone
• Non-resorbable structure that provides osseointegration
• Less inflammatory than normal hydroxyapatite
• Leads to increased production of bone alkaline phosphatase and osteocalcin, indicating increased bone production

READY TO USE

• Histomorphometric analysis shows 42% newly formed bone, 21% nano-hydroxyapatite, and 37% medullary spaces.
• This result was obtained with FISIOGRAFT NANO HA REINFORCED just four months after surgery.
• This value is comparable to results obtained with autologous bone or other space maintainers after 6–8 months as stated in the literature (2, 3).

ADVANTAGES OF FISIOGRAFT NANO HA REINFORCED

• RESORPTION + OSSEOINTEGRATION
• PLGA degradation within 3–6 months to make room for newly formed bone
• Hydroxyapatite integrates with the mineralized structure of bone
• NO RISK: BSE – HIV – HBV – SARS
• High biocompatibility
• Easy application