{"product_id":"ibi-sa-smartbone-bone-regeneration-bone-graft-2gr","title":"Ibi Sa SmartBone Bone Regeneration - Bone Graft 2 g","description":"\u003cdiv class=\"dr-product-desc\"\u003e\n\u003cstyle\u003e\n  .dr-product-desc{font-size:15px;line-height:1.7;color:#3a3a3a;max-width:100%;word-wrap:break-word}\n  .dr-product-desc .section-title{font-size:1.1em;font-weight:700;margin:1.75em 0 .65em;padding:8px 12px 8px 14px;border-left:4px solid #0077c8;color:#1a1a1a;line-height:1.35;background:#eef6fb}\n  .dr-product-desc .section-title:first-of-type{margin-top:0}\n  .dr-product-desc p{margin:0 0 .9em;line-height:1.7}\n  .dr-product-desc ul{margin:.25em 0 1em;padding-left:1.3em}\n  .dr-product-desc li{margin-bottom:.45em;line-height:1.65}\n  .dr-product-desc strong{font-weight:600;color:#222}\n  .dr-product-desc .key-highlight{background:linear-gradient(135deg,#f0f7ff 0%,#e8f4fc 100%);border:1px solid #b8d9f0;border-left:5px solid #0077c8;border-radius:10px;padding:20px 22px 18px;margin:1.75em 0;box-shadow:0 2px 12px rgba(0,119,200,.08)}\n  .dr-product-desc .key-highlight::before{content:\"What sets this product apart\";display:inline-block;font-size:.72em;font-weight:700;letter-spacing:.04em;text-transform:uppercase;color:#fff;background:#0077c8;padding:5px 12px;border-radius:4px;margin-bottom:12px}\n\u003c\/style\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eSmartBone Bone Graft — Bovine Origin — 2 g\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eA bone graft born from advanced tissue-engineering technology\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSmartBone®, SmartBone® ORTHO, SmartBone® On Demand™ and SwissBone® are produced by combining natural mineral bone structures with bioabsorbable polymers and collagen fragments. This biomaterial combination concept allows the patient’s cells to replace bone quickly and efficiently as the biopolymers degrade, delivering excellent integration and osteogenesis. Thanks to this technology the graft mimics human bone, is mechanically strong, and withstands shaping, screws, and surgical fixation maneuvers.\u003c\/p\u003e\n\u003cp\u003eSmartBone®, SmartBone® ORTHO, SmartBone® On Demand™ and SwissBone® are essentially the same products under different brand names or use indications.\u003c\/p\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eBovine bone matrix\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHas a chemical structure and morphology similar to human bone\u003c\/li\u003e\n\u003cli\u003eIs hard but not elastic and therefore quite brittle (because the mineral matrix loses its biomechanical properties when proteins are lost during cleaning processes)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eBioabsorbable polymers\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHigh load resistance\u003c\/li\u003e\n\u003cli\u003eHigh volumetric stability (\u0026gt;95%); polymers protect the bone from early resorption\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eCollagen fragments\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ePromote adhesion and colonization of blood cells\u003c\/li\u003e\n\u003cli\u003eGuarantee high hydrophilicity and thus enhance the biochemical signaling cascade that supports the osteoinductive process\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eHuman-like microstructure\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe microstructure of the SmartBone® \/ ORTHO \/ On Demand™ \/ SwissBone® composite matrix strongly resembles human bone in open, interconnected, medium-sized porosity. It mimics the properties of healthy human bone: high biocompatibility, adequate open porosity, high mechanical performance, hydrophilicity. These grafts are designed to reduce the intrinsic variability of many other bone substitutes of natural origin. IBI offers homogeneous bone substitutes with regular microstructure, porosity, density, and mechanical properties.\u003c\/p\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eVery high hydrophilicity and rapid osseointegration\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThanks to its microcomposition, SmartBone® quickly reaches about 38% w\/w blood swelling, triggering the chemical signaling cascade that drives strong osseointegration. Microstructure and composition support cell colonization.\u003c\/p\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eIn vitro and in vivo studies\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eElectron microscopy of in vitro cell colonization tests showed extensive, well-structured cell formations within SmartBone® products, confirming biochemical data collected in vitro under ISO standards. Biological and histological research showed how supportive these bone substitutes are for cell adhesion and growth; mesenchymal stem cells derived from human adipose tissue colonized the scaffold appropriately in vitro and differentiated once stimulated. In vivo studies over a 4-month observation period confirmed integration by natural bone formation including cells and vessels colonizing the pores over time.\u003c\/p\u003e\n\u003cp class=\"section-title\"\u003e\u003cstrong\u003eDental indications and handling advantages\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEasy, dust-free shaping with any surgical instrument (e.g. bone cutter, drill)\u003c\/li\u003e\n\u003cli\u003eResistant to heavy loads and heavy surgical maneuvers\u003c\/li\u003e\n\u003cli\u003eMuch better stability of an expanded bone graft versus loose granules\u003c\/li\u003e\n\u003cli\u003eLarger defects do not require autologous bone, reducing patient morbidity\u003c\/li\u003e\n\u003cli\u003eNo early resorption: polymeric coating protects the graft during the first healing\/osseointegration period\u003c\/li\u003e\n\u003cli\u003eAbsorbs blood easily\u003c\/li\u003e\n\u003cli\u003eRegeneration of periodontal bone defects\u003c\/li\u003e\n\u003cli\u003eRegeneration of extraction sockets\u003c\/li\u003e\n\u003cli\u003eRegeneration of gaps between the alveolar wall and immediate implants\u003c\/li\u003e\n\u003cli\u003eHorizontal alveolar ridge augmentation\u003c\/li\u003e\n\u003cli\u003eSinus lift floor elevation\u003c\/li\u003e\n\u003cli\u003eAlveolar ridge augmentation at implant sites with adequate residual bone and good blood supply\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Ibi Sa","offers":[{"title":"0.25 - 1.0 mm","offer_id":42335996608556,"sku":"SMG251020","price":244.0,"currency_code":"USD","in_stock":true},{"title":"1.0 - 2.0 mm","offer_id":42335996641324,"sku":"SMG102020","price":244.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2699\/7450\/files\/smartbone2grsite.jpg?v=1734957862","url":"https:\/\/www.dentrealstore.com\/en-de\/products\/ibi-sa-smartbone-bone-regeneration-bone-graft-2gr","provider":"DentrealStore","version":"1.0","type":"link"}